Ldk378 ic50
WebChemsrc provides LDK378 (dihydrochloride)(CAS#:1380575-43-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of LDK378 ... Ceritinib dihydrochloride (LDK378 dihydrochloride) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively ... WebGilteritinib (ASP2215) 是一种有效的 ATP 竞争性的 FLT3/AXL 抑制剂，IC50 分别为 0.29 nM/0.73 nM ... 2024-09-06 10:07 385. Ceritinib (LDK378) 是一种选择性，具有口服活性的且具有 ATP 竞争性的 ALK ...
Ldk378 ic50
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WebLDK378 is a highly potent inhibitor of anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase belonging to the superfamily of insulin receptor, with half maximal inhibitory concentration IC50 of 200 pM. LDK378 also exhibits modest to hig WebLDK378 is a highly potent inhibitor of anaplastic lymphoma kinase (ALK), which is a receptor tyrosine kinase belonging to the superfamily of insulin receptor, with half maximal inhibitory concentration IC50 of 200 pM. LDK378 also exhibits modest to high inhibition against a panel of other kinases, in which only three kinases with IC50 below 100 ...
WebLDK378 是一种选择性，具有口服活性的、ATP 竞争性的ALK酪氨酸激酶抑制剂，IC50=200 pM。 它还抑制IGF-1R (IC50:8 nM)，InsR (IC50:7 nM) 和 STK22D (IC50:23 nM)。 它 … WebCeritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib dihydrochloride (LDK378 dihydrochloride) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively.
Web10 jul. 2024 · product name Ceritinib (LDK378) Description: Ceritinib (also known as LDK378) is potent and selective inhibitor against ALK with IC50 of 0.2 nM in cell-free … WebCeritinib (LDK378) is a specific ALK inhibitor (IC50: 0.2 nM). Home Tools. Log in. Products Inhibitors Libraries Kits Services Contact Us. Cart. The Shopping Cart is Empty!
WebLDK378 dihydrochloride (LDK378 dihydrochloride) 是一种选择性、口服生物利用度和 ATP 竞争性的 ALK 酪氨酸激酶抑制剂，IC50 为 200 pM。 GlpBio Products Cited In Reputable Papers Nature 610.7931 (2024): 366-372 Cell 183.7 (2024): 1867-1883 Cell Research (2024): 1-17 Molecular Cancer 21.1 (2024): 1-17 Molecular Cancer 21.1 (2024): 1-18 …
WebConclusion: The polymorphisms of IFN-γ+874 may have no influence on LDK378 ic50 the susceptibility to UC. Genotypes may be the determinants 上海皓元 of their corresponding serum levels in healthy adult people, however, the serum levels in UC patients were also influenced by other hoary rock roseWeb6 jan. 2024 · Ceritinib (LDK378) shows potent antiproliferative activity with an IC50 value of 22.8 nM in Karpas 299 human non-Hodgkin’s Ki-positive large cell lymphoma carrying … hoary skullcapWebLDK378 is a selective small molecule inhibitor of ALK, a target found in metastatic non-small cell lung cancer (NSCLC). LDK378 shows great anti-proliferative activity in Ba/F3-NPM … hr law certificateWeb16 March 2024—Buy LDK378 dihydrochloride,Cas No.:1380575-43-8, MOQ 1 gram, Molecular Formula:C28H38Cl3N5O3S ,Molecular Weight:631.06, ... LDK378 2Hcl … hrlawlogix comWeb8 jan. 2014 · LDK378 is a highly selective and potent inhibitor of ALK, and has demonstrated preclinical antitumor activity against tumors with acquired crizotinib … hoary rock-roseWebCeritinib (LDK378),a potent inhibitor against ALK with IC50 of 0.2 nM. ... (LDK378) Reagents: Molecular Biology Biochemistry Cell Biology ELISA / Diagnostic Kits Antibody … hoary stock maintenanceWeb20 mei 2012 · Background: LDK378 is a novel, potent and selective small molecule anaplastic lymphoma kinase (ALK) inhibitor (IC 50 0.00015 μM), that does not inhibit c … hoary ragwort identification