Human ccl17
Web27 jun. 2024 · CCL17/TARC is a chemokine that interacts with CCR4 and CCR8 to induce the chemoattraction of activated Th2 cells, basophils, and NK cells. It is produced by thymic dendritic cells, lymph node dendritic cells, monocytes, CD4+ T cells, keratinocytes, fibroblasts, bronchial epithelial cells, and Reed-Sternberg cells. WebThe genes for CCL17 and CCL22 are located on human chromosome 16q13, tightly linked to CX3CL1. The CCL17 gene (2176 bp) comprises 4 exons and encodes a 94 amino acid pre-protein with a 23 amino acid signal sequence. The CCL17 and CCL22 proteins contain four cysteine residues characteristic of all CC-chemokines and they share 32% amino …
Human ccl17
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WebThis recombinant Human CCL17 can be used to create a standard curve in a sandwich ELISA with purified Mouse anti Human CCL17 antibody, clone I02-2A4 ( MCA6180GA) as the capture antibody and biotinylated Mouse anti Human CCL17 antibody, clone I11-2A1 ( MCA6181B) as the detection antibody. Product Details Target Species Human Product … WebProduct Description. Rabbit anti Human CCL17 antibody specifically recognizes human CCL17, otherwise known as TARC (thymus and activation-regulated chemokine), a member of the intercrine beta (chemokine CC) family, predominantly produced by thymic dendritic cells, which specifically acts as a chemotactic factor for T cells, and signals through ...
WebCCL17 is a novel CC chemokine identified using a signal sequence trap method. CCL17 cDNA encodes a highly basic 94 amino acid (aa)residue precursor protein with a 23 aa residue signal peptide that is cleaved to generate the 71 aa residue mature secreted protein. WebCCL17 knockdown significantly inhibited CCL17 release, CCR4 expression, and the cell proliferation of CAFs, while CCL17 overexpression demonstrated an inverse effect in NFs. Co-culture with CAFs induced the increases in cell proliferation, migration, invasion, and the expression of CCL17, CCR4, MMP13, and p-ERK1/2 in MCF-7 and MDA-MB-231 cells …
WebChemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine (TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the … WebTARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking ...
WebThe present invention is in the field of amyotrophic lateral sclerosis (ALS) and relates to human interleukin-2 (IL-2) for use in the treatment of amyotrophic lateral sclerosis in
WebSimple Plex Human CCL17/TARC assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. SPCKB-PS-000194. 3 Images. Show Size & Price. Human CCL17/TARC DuoSet ELISA . DY364. 19 Citations. 2 Reviews. 1 Image. ELISA. Show Size & Price. Recombinant Human CCL17/TARC Protein . 364-DN. 16 Citations. … the oakley arms maentwrogWebTarget Information. TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. the oakley apartments delawareWebHuman CCL17, also known as thymus and activation regulated chemokine (TARC), was initially isolated from phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 is constitutively expressed in the thymus and under activation in several cell types. the oakley arms brewood staffordshireWebHuman TARC ELISA Kit (CCL17) (ab183366) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of TARC protein in human cell culture supernatants, serum and plasma samples. It uses our proprietary SimpleStep ELISA® technology. Quantitate human TARC with 78.5 pg/mL sensitivity. the oakley apartments arlington txWebTARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. the oakley eventsWebCCL17/TARC is a chemokine that interacts with CCR4 and CCR8 to induce the chemoattraction of activated Th2 cells, basophils, and NK cells. It is produced by thymic dendritic cells, lymph node dendritic cells, monocytes, CD4+ T cells, keratinocytes, fibroblasts, bronchial epithelial cells, and Reed-Sternberg cells. the oakley arms walesWebImmunogen: Human CCL17 Recombinant Protein Application: Intracellular staining (flow cytometry) (Routinely Tested) Concentration: 0.2 mg/ml RRID: AB_2739473 Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. Regulatory Status: RUO View All Formats Preparation And Storage the oakley court windsor england